PRFM stands for platelet rich fibrin matrix. PFRM contains PRP (platelet rich plasma). PRFM is contains a rich fibrin matrix that nourishes and contains platelets near the injection site. By keeping these platelets where they need to be, the release of growth factors (including stem cells) is locally concentrated and lasts longer. This then drives cellular growth, reduced healing time and stimulation of collagen production.
Typically, our provider will draw 2-4 vials of blood and place them in a centrifuge to spin for 6 minutes
causing the components to separate. When that process is done the PRP (and thus PRFM) can be harvested and injected in the desired area.
The injections are relatively quick with very little pain at the injection site. A warm flushing feeling is typically felt as the PRFM is injected. This is a result of the changes that start to take place immediately, and a good sign that the growth factors are already working!
PRP has very minimal downtime. For a few days you may have a small bit of swelling and possibly bruising. It is very similar to the downtime of other injectables like Botox and fillers.
There are multiple practitioners and systems that offer PRP but not PRFM. We can use a
system that maximizes the harvest of growth factors, including stem cells, from a closed system which maximizes results. Usually we wait 8-12 weeks to really see a difference.
People with a history of thrombocytopenia, hypofibrinogenaemia, sepsis, chronic liver disease, cancer and those on anti-coagulation therapy are not candidates for this procedure. We also advise patients who may not appreciate the full result to consider other options like laser and surgery if we feel they are better candidates. Finally, anyone considering PRP or PFRM or any “regenerative” procedure must understand that these treatments are experimental. While they have gained mainstream popularity and attention, we ask all patients to do their homework on the topic first.